“Even when clinicians deal with these issues on a regular basis, how often do we really think about them? This is a refresher on things we think we know but may not actually remember correctly,” said David Borenstein, MD.

Kawasaki disease is most likely a rheumatologic condition associated with an overactive immune response to infection. And while the disease has long been viewed as being driven by TNF, new findings implicate interleukin 1β.

The latest investigative approaches can look at individual genes within single cells, multiplied by thousands of cells for each of hundreds of healthy and diseased subjects. These new hypothesis generating studies can reveal novel and surprising truths about physiology and pathophysiology.

“Recent evidence implicates neutrophil dysregulation in the pathogenesis of various systemic autoimmune diseases and associated organ damage,” said Mariana Kaplan, MD.

In The Rheum sessions have been designed so leading experts can talk about the most important and somewhat controversial topics facing the rheumatology community.

This year’s session will highlight the latest scientific evidence and best practices about three challenging conditions managed by rheumatologists

What makes ACR Masters tick? What motivations and pivotal decisions have shaped their careers and led to their success? A new networking session, Meet the Master: Journey Behind the Success, offers an up-close-and-personal opportunity to learn about their journeys.

The annual Thieves’ Market: Show Me Your Best Cases once again will feature a variety of fascinating, mysterious and/or uncommon clinical rheumatology cases. And this year, there will be a second session devoted to pediatric cases.

“Our goal is to offer ACR members and the rheumatology community at large, thought-provoking and quality content they can consistently access on the go,” said podcast host Jonathan Hausmann, MD.

Dr. Solomon is professor of medicine at Harvard Medical School and Chief of the Section of Clinical Sciences in the Division of Rheumatology at Brigham and Women’s Hospital.